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Northumberland begin their Minor Counties Championship programme with a home game against Norfolk at Jesmond.
Brothers Paul and Matthew Muchall will feature for the first time this season, while former Bedfordshire all-rounder David Myers is set to make his debut.
Captain Phil Nicholson will play as a specialist batsman due to an ongoing finger problem, allowing Richard Coughtrie to continue as wicketkeeper.
Still smarting from a five-run defeat against the same county three weeks ago in the MCCA Knockout Trophy, Northumberland will be keen to reverse the result.
Northumberland team: Phil Nicholson (captain), Allan Worthy, Paul Muchall, David Myers, Bradley Parker, Marc Symington, Graham Bridge, Richard Coughtrie, David Rutherford, Matthew Muchall, Gary Stewart.
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